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Proteasome inhibition can impair caspase-8 activation upon submaximal stimulation of apoptotic tumor necrosis factor-related apoptosis inducing ligand (TRAIL) signaling
Authors:Laussmann Maike A  Passante Egle  Hellwig Christian T  Tomiczek Bartlomiej  Flanagan Lorna  Prehn Jochen H M  Huber Heinrich J  Rehm Markus
Affiliation:Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Abstract:
Keywords:Apoptosis   Caspase   Cell Death   Signal Transduction   Systems Biology   Förster Resonance Energy Transfer (FRET)   Tumor Necrosis Factor-related Apoptosis Inducing Ligand (TRAIL)   Bortezomib   Caspase-8   Proteasome Inhibition
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