An efficient algorithm to compute the posterior genotypic distribution for every member of a pedigree without loops |
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| Authors: | R. L. Fernando C. Stricker R. C. Elston |
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| Affiliation: | (1) Department of Animal Sciences, University of Illinois at Urbana-Champaign, 1207 West Gregory Drive, 61801 Urbana, IL, USA;(2) Department of Biometry and Genetics, Louisiana State University, Medical Center, 1901 Perdido Street, 70112-1393 New Orleans, USA |
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| Abstract: | This paper describes a non-iterative, recursive method to compute the likelihood for a pedigree without loops, and hence an efficient way to compute genotype probabilities for every member of the pedigree. The method can be used with multiple mates and large sibships. Scaling is used in calculations to avoid numerical problems in working with large pedigrees. |
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| Keywords: | Genotype probabilities Likelihood Recursive algorithm |
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