Acquisition and processing of a conditional dicentric chromosome in Saccharomyces cerevisiae. |
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| Authors: | A Hill and K Bloom |
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| Institution: | Department of Biology, University of North Carolina, Chapel Hill 27599-3280. |
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| Abstract: | The introduction of a conditional centromere into chromosome III of Saccharomyces cerevisiae provided an opportunity to evaluate phenotypic and karyotypic consequences in cells harboring dicentric chromosomes upon entry into mitosis. A mitotic pause ensued, and monocentric derivatives of chromosome III were generated at a high frequency. |
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