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Reorganization of cytoskeleton as a basis of morphogenesis |
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| Authors: | Ju M Vasiliev |
| Institution: | (1) Research Institute of Physicochemical Biology, Moscow State University, Leninskie gory, Moscow, 119992, Russia;(2) Research Institute of Carcinogenesis, Blokhin Russian Oncological Center of the Russian Academy of Medical Sciences, Kashirskoe sh. 24, Moscow, 115478, Russia |
| Abstract: | A brief review of the cytoskeleton dynamic structure in cells of two types: fibroblasts and epitheliocytes. Differences have been described between the functions of γ-actin filaments and β-actomyosin bundles. Tubulogenesis and angiogenesis have been considered as consequences of partial epitheliomesenchymal transformation and neoplastic transformation as a consequence of γ-actomyosin bundles disturbance. |
| Keywords: | cytoskeleton fibroblast epitheliocyte actin myosin epitheliomesenchymal transformation neoplastic transformation |
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