Microrheological characteristics of reticulocyte in vivo |
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Authors: | Lide Xie Dagong Sun Weijuan Yao Zongyao Wen |
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Institution: | (1) Hemorheology Center, Department of Biophysics, School of Basic Medical Sciences, Peking University, 100083 Beijing, China |
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Abstract: | Using the method of phenylhydrazine-induced anemia in rabbits, a mass of new reticulocytes, which synchronously grow, were
got in vivo. The measurements of deformation index, orientation index, electrophoresis mobility etc. were performed for more than 72
h in the process of reticulocytes turning into red blood cells in vivo. There were obvious changes in the microrheological characteristics of reticulocytes in the course of turning into erythrocytes.
The present study is significant in clinic for studying erythrocytes’ microrheological characteristics when there are a lot
of reticulocytes in blood, and also important in basic theorem for studying reticulocytes microrheological characteristics.
It makes up a deficiency in the study on microrheological characteristics of reticulocytes turning into new RBCs from reticulocytes
during reticulocytes life span. |
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Keywords: | phenylhydrazine reticulocyte microrheological characteristics deformation indexes orientation indexes new ektacytometry |
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