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| 明胶/纳米SiO2复合膜的体外抑菌试验 | |
| 引用本文： | 代 敏,郭文宇,王雄清,彭 成,陈希文,杨丽红,杨 蕾. 明胶/纳米SiO2复合膜的体外抑菌试验[J]. 微生物学通报, 2008, 35(10): 1532-1537 |
| 作者姓名： | 代 敏 郭文宇 王雄清 彭 成 陈希文 杨丽红 杨 蕾 |
| 作者单位： | 1. 绵阳师范学院动物应用技术研究所,分子生物学与生物制药重点实验室,绵阳,621000;成都中医药大学药学院,成都,610075 2. 绵阳师范学院动物应用技术研究所,分子生物学与生物制药重点实验室,绵阳,621000 3. 成都中医药大学药学院,成都,610075 |
| 基金项目： | 四川省教育厅资助项目，绵阳师范学院校科研和教改项目 |
| 摘 要： | 本实验测定了明胶、纳米SiO2、明胶/纳米SiO2复合膜对6种供试菌的抑菌效果,结果表明,明胶不具有抑菌作用;纳米SiO2对供试菌具有较好的抑茵效果;20种明胶/纳米SiO2复合膜材料中,有11种复合膜对供试菌具有较强的抑菌效果.用琼脂平板稀释法测定了具有较强抑菌作用复合膜的最低抑菌浓度(MIC),结果表明,最低抑菌浓度因膜的配比和菌种类型的不同而有所差异,为16.0 mg/mL～256.0 mg/mL.复合膜对蜡样芽孢杆菌的最低抑菌浓度(MIC)最大(256.0 mg/mL),而对其他供试菌相对较低,为64.0 mg/mL～128.0 mg/mL. |
| 关 键 词： | 抑菌试验 纳米SiO2 明胶 复合膜 |
Bacteriostatic Test in vitro of the Gelatin/Nano-SiO2 Composite Membrane |
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| DAI Min,GUO Wen-Yu,WANG Xiong-Qing,PENG Cheng,CHEN Xi-Wen,YANG Li-Hong and YANG Lei. Bacteriostatic Test in vitro of the Gelatin/Nano-SiO2 Composite Membrane[J]. Microbiology China, 2008, 35(10): 1532-1537 | |
| Authors: | DAI Min GUO Wen-Yu WANG Xiong-Qing PENG Cheng CHEN Xi-Wen YANG Li-Hong YANG Lei |
| Affiliation: | (1. Institute of Applied Animal Technology, Key Laboratory for Molecular Biology and Biopharmaceuticals, Mianyang Normal University, Mianyang 621000) (2.College of Pharmaceuticals, Chengdu University of Traditional Chinese Medicine, Chengdu 610075);Institute of Applied Animal Technology, Key Laboratory for Molecular Biology and Biopharmaceuticals, Mianyang Normal University, Mianyang 621000;Institute of Applied Animal Technology, Key Laboratory for Molecular Biology and Biopharmaceuticals, Mianyang Normal University, Mianyang 621000;College of Pharmaceuticals, Chengdu University of Traditional Chinese Medicine, Chengdu 610075;Institute of Applied Animal Technology, Key Laboratory for Molecular Biology and Biopharmaceuticals, Mianyang Normal University, Mianyang 621000;Institute of Applied Animal Technology, Key Laboratory for Molecular Biology and Biopharmaceuticals, Mianyang Normal University, Mianyang 621000;Institute of Applied Animal Technology, Key Laboratory for Molecular Biology and Biopharmaceuticals, Mianyang Normal University, Mianyang 621000 |
| Abstract: | The paper studied antibacterial effects in vitro of gelatin, nano-SiO2 and gelatin/nano-SiO2 composite membranes on 6 kinds of bacteria. The results indicated that gelatin had no antibacterial effect; nano-SiO2 had antibacterial effect; 11 out of 20 kinds of gelatin/nano-SiO2 composite membranes had strong antibacterial effects. Their minimal inhibitory concentrations (MICs) were also tested using the method of plate dilution, and the results indicated that they had different MICs because of different membranous formula and different bacteria. There were differences of MICs for different bacteria. For Bacillus cereu, MIC was 256.0 mg/mL; but for other bacteria, MICs were mainly 64.0 mg/mL-128.0 mg/mL. |
| Keywords: | Bacteriostatic test Nano-SiO2 Gelatin Composite membrane |
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