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Action of antioxidants on membrane-toxic effects of anticholinesterase agents |
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| Authors: | E P Zatsepin N N Churaev T A Uspenskaia G D Tirzit G Ia Dubur |
| Abstract: | It was found therapeutic-preventive effectiveness of antioxidants (1,4-dihydropyridine derivatives) at poisoning with malathion insecticide. The effect of 1,4-dihydropyridine derivatives can be attributed to a prevention of lipid peroxidation. Antioxidants do not affect the toxicity of 0,0-dimethyl-0-2,2-dichlorvinylphosphate. Thus, antioxidants are pathogenetic drugs for treatment of poisonings with cholinesterase inhibitors. |
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