| 昆虫杆状病毒泛素基因研究进展 |
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| 引用本文： | 李朝飞,李充璧,余健秀,庞义. 昆虫杆状病毒泛素基因研究进展[J]. 中国生物工程杂志, 2001, 21(6): 28-30 |
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| 作者姓名： | 李朝飞 李充璧 余健秀 庞义 |
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| 作者单位： | 中山大学生物防治国家重点实验室 广州 510275 |
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| 基金项目： | 国家自然科学基金资助重点项目(39730030)和"973"计划项目(G2000016209)资助. |
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| 摘 要： | 昆虫杆状病毒是目前已知唯一编码泛素(ubiquitin)的病毒。迄今,已克隆了8种该类病毒的泛素基因。与真核生物Uba52(80)相似,这些基因在一个泛素分子的C末端都有不同长度的融合,其中斜纹夜蛾核多角体病毒(Spodopteralituramulticapsidnucleopolyhedrovirus,SpltMNPV)的ubiquitingp37基因是一个典型的融合基因。近年来,对苜蓿银纹夜蛾核多角体病毒(Autographacaliforniamulticapsidnucleopolyhedrovirus,AcMNPV)泛素的定位与功能研究取得了重要进展 。
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| 关 键 词： | 昆虫杆状病毒 泛素 ubiquitin基因 |
Progress in the Studies of Ubiquitin Genes of Insect Baculoviruses |
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| Li Zhao-fei Li Chong-bi Yu Jian-xiu Pang Yi. Progress in the Studies of Ubiquitin Genes of Insect Baculoviruses[J]. China Biotechnology, 2001, 21(6): 28-30 |
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| Authors: | Li Zhao-fei Li Chong-bi Yu Jian-xiu Pang Yi |
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| Abstract: | Insect baculovirus are the only viruses currently known to encode ubiquitin homologies. At present, seven ubiquitin genes of different insect baculoviruses were cloned. Similarly to Uba52(80) genes of eukaryotes, different length amino acids are fused at the C-terminus of baculovirus ubiquitins. Among them, Spodoptera litura multicapsid nucleopolyhedrovirus (SpltMNPV) ubi-gp37 is a typical ubiquitin fusion gene. Recently, great progress was made in studying on the position and function of Autograph californica multicapsid nucleopolyhedrovirus (AcMNPV) ubiquitin. |
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| Keywords: | Insect baculoviruses Ubiquitin genes |
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