Chronic recurrent vulvovaginitis is not only due to Candida |
| |
Affiliation: | 1. Centro de Estudios Micológicos, Ciudad Autónoma de Buenos Aires, Argentina;2. Unidad Micología del Hospital de Infecciosas F. J. Muñiz, Ciudad Autónoma de Buenos Aires, Argentina |
| |
Abstract: | BackgroundRecurrent vulvovaginitis is a growing problem that affects millions of women worldwide. In many cases it is treated as vulvovaginal candidiasis, but there is not always microbiological confirmation.AimsTo determine the etiology of vulvovaginitis in a group of patients.MethodsThis is a cross-sectional study in which the data from the medical records of 316 adult patients who consulted for vulvovaginitis were analyzed. Eighty nine percent of the cases had already suffered previous episodes.ResultsThe median age was 34 (265 patients were between 16 and 45 years old). Yeasts were isolated in culture from 211 (66.8%) patients, although pseudo-hyphae and yeasts were observed in only 166 samples (52.5%) in the direct microscopic examination. Multiple predisposing factors were found, among which the use of contraceptives or previous antibiotics stand out. Most of the patients (almost 90%) had been treated with antifungals, with or without microbiological confirmation. Candida albicans was isolated in 187 (88.6%) patients, followed by Candida glabrata in 6 (2.8%) patients. Association with bacterial vaginosis was found in 35.1% and with intermediate bacterial microbiota in 33.2% of the cases. A remarkably high proportion of C. albicans isolates resistant to fluconazole (80.1%) and itraconazole (58.8%) was found.ConclusionsA microbiological analysis is essential to confirm the diagnosis of vulvovaginal candidiasis, whether simple, complicated, or recurrent. Identifying the isolated yeast species and determining its susceptibility to antifungal agents are particularly important. |
| |
Keywords: | Vulvovaginal candidiasis Vulvovaginitis Candidiasis vulvovaginal Vulvovaginitis |
本文献已被 ScienceDirect 等数据库收录! |
|