| Wonder or evil?: Multifaceted health hazards and health benefits of Cannabis sativa and its phytochemicals |
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| 摘 要： |
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| 收稿时间： | 18 December 2020 |
Wonder or evil?: Multifaceted health hazards and health benefits of Cannabis sativa and its phytochemicals |
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| Authors: | Shivika Datta Praveen C Ramamurthy Uttpal Anand Simranjeet Singh Amritpal Singh Daljeet Singh Dhanjal Vaishali Dhaka Sanjay Kumar Dhriti Kapoor Samapika Nandy Manoj Kumar Eapen P Koshy Abhijit Dey Jaros&#x;aw Pro&#x;kw Joginder Singh |
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| Institution: | 1. Department of Zoology, Doaba College, Jalandhar, Punjab 144001, India;2. Interdisciplinary Centre for Water Research (ICWaR), Indian Institute of Sciences, Bangalore 560012, Karnataka, India;3. Department of Molecular and Cellular Engineering, Jacob Institute of Biotechnology and Bioengineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj 211007, Uttar Pradesh, India;4. Department of Oral and Maxillofacial Surgery, Indira Gandhi Government Dental College and Hospital, Amphala, Jammu 180012, India;5. Department of Biotechnology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab 144411, India;6. Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Miyagi 980-8577, Japan;7. Department of Botany, Lovely Professional University, Phagwara, Punjab 144411, India;8. Department of Life Sciences, Presidency University, Kolkata 700073, West Bengal, India;9. Department of Life Sciences, School of Natural Science, Central University of Jharkhand, Brambe, Ratu-Lohardaga Road Ranchi, Jharkhand 835205, India;10. Department of Plant Biology, Institute of Environmental Biology, Wrocław University of Environmental and Life Sciences, Kożuchowska 5b, 51-631 Wrocław, Poland |
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| Abstract: | Cannabis sativa, widely known as ‘Marijuana’ poses a dilemma for being a blend of both good and bad medicinal effects. The historical use of Cannabis for both medicinal and recreational purposes suggests it to be a friendly plant. However, whether the misuse of Cannabis and the cannabinoids derived from it can hamper normal body physiology is a focus of ongoing research. On the one hand, there is enough evidence to suggest that misuse of marijuana can cause deleterious effects on various organs like the lungs, immune system, cardiovascular system, etc. and also influence fertility and cause teratogenic effects. However, on the other hand, marijuana has been found to offer a magical cure for anorexia, chronic pain, muscle spasticity, nausea, and disturbed sleep. Indeed, most recently, the United Nations has given its verdict in favour of Cannabis declaring it as a non-dangerous narcotic. This review provides insights into the various health effects of Cannabis and its specialized metabolites and indicates how wise steps can be taken to promote good use and prevent misuse of the metabolites derived from this plant. |
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| Keywords: | Tetrahydrocannabinol Cannabinoids Psychoactive Medical marijuana Phytochemicals Chemical components Therapeutic roles |
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