Prevalence and predictors of non-alcoholic fatty liver disease in tertiary care hospital of Taif,Saudi Arabia: A retrospective study |
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Authors: | Abdulhakeem S Alamri Majid Alhomrani Walaa F Alsanie Ahmad Joman Alghamdi Zaher M Alghamdi Abdualmohsen A Al-Subaie Yasser A Alharthi Hesham H Alqurashi Syed Mohammed Basheeruddin Asdaq |
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Institution: | 1. Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia;2. Centre of Biomedical Sciences Research (CBSR), Deanship of Scientific Research, Taif University, Saudi Arabia;3. Department of Radiology, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia;4. Department of Hepatology, King Abdulaziz Specialist Hospital, Taif, Saudi Arabia;5. Department of Pharmacy Practice, College of Pharmacy, AlMaarefa University, Dariyah, 13713 Riyadh, Saudi Arabia |
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Abstract: | BackgroundThe prevalence of nonalcoholic fatty liver disease (NAFLD) in Saudi Arabia is predicted to exceed 30% by 2030. NAFLD leads to liver fibrosis, thus increasing morbidity and health care burden. Obesity and diabetes have been strongly associated with NAFLD in different cities in Saudi Arabia.ObjectivesTherefore, we aim to determine the prevalence rate of NAFLD and specific risk factors for NAFLD among patients of tertiary care hospital of Taif city.Material and methodsWe retrospectively analyzed the medical records of patients for two years, between Feb 2017 and Feb 2019, (n = 100) referred to the hepatology clinic at King Abdulaziz Specialist Hospital in Taif. The diagnosis of NAFLD was based on the radiology report for patients who were aged >20 years old. Other parameters including fasting blood glucose (FBG), platelets count, alanine transaminase (ALT), aspartate transaminase (AST) and total bilirubin were statistically analyzed.ResultsWe found that 40% (P < 0.05) of all patients had NAFLD. The results revealed that a significantly high number of patients with NAFLD have high FBG levels (75%, P < 0.0001) and total bilirubin (P < 0.05). Meanwhile, platelet count was significantly reduced in patients with NAFLD (P < 0.05).ConclusionNAFLD can be a serious health problem in the Taif region. In addition, high FBG is a significant specific risk factor for NAFLD. Health care providers should pay more attention to limiting the prevalence of NAFLD and its risk factors. |
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Keywords: | Nonalcoholic fatty liver disease Obesity Type 2 diabetes Risk factors Age Fasting blood glucose |
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