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FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner
Affiliation:1. Institut de recherches cliniques de Montréal, 110 Avenue des Pins Ouest, Montréal, QC H2W 1R7, Canada;2. Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK;3. Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA;4. Department of Molecular Biology and Genetics, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA;5. Département de Médecine, Faculté de Médecine, Université de Montréal, 2900 Boulevard Édouard-Montpetit, Montréal, QC H3T 1J4, Canada
Abstract:
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  • Keywords:histone chaperone  FACT  Spt16  Pob3  Chd1  RNA polymerase II  nucleosome unwrapping  chromatin remodeling  single-molecule tracking  mathematical modeling
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