The renaissance of GSK3 |
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| Authors: | Cohen P Frame S |
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| Affiliation: | MRC Protein Phosphorylation Unit and Division of Signal Transduction Therapy, School of Life Sciences, University of Dundee, DD1 5EH, Scotland, UK. p.cohen@dundee.ac.uk |
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| Abstract: | Glycogen synthase kinase 3 (GSK3) was initially described as a key enzyme involved in glycogen metabolism, but is now known to regulate a diverse array of cell functions. The study of the substrate specificity and regulation of GSK3 activity has been important in the quest for therapeutic intervention. |
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