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Use of nanocolonies to detect minimal residual disease in patients with leukemia t(8;12)
Authors:Falaleeva  M V  Chetverina  H V  Kravchenko  A V  Chetverin  A B
Institution:(1) Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia
Abstract:Molecular Biology - A complete diagnostic procedure was developed to detect single molecules of the AML1-ETO mRNA in whole blood and bone marrow samples of leukemia t(8;21)(q22;q22) patients. The...
Keywords:acute myeloid leukemia  chromosomal translocation t(8  21)  chimeric AML1-ETO mRNA  minimal residual disease  RNA isolation from blood and bone marrow  RT-PCR  nanocolonies  molecular colonies  polonies
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