Identification of multiple independent horizontal gene transfers into poxviruses using a comparative genomics approach |
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Authors: | Kirsten A Bratke Aoife McLysaght |
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Affiliation: | (1) Smurfit Institute of Genetics, University of Dublin, Trinity College, Dublin 2, Ireland |
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Abstract: | Background Poxviruses are important pathogens of humans, livestock and wild animals. These large dsDNA viruses have a set of core orthologs whose gene order is extremely well conserved throughout poxvirus genera. They also contain many genes with sequence and functional similarity to host genes which were probably acquired by horizontal gene transfer. |
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