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Studies on the PR toxin of penicillium roqueforti
Authors:L Polonelli  G Morace  F Delle Monache  R A Samson
Institution:(1) Istituto di Microbiologia, Universita' Cattolica del Sacro Cuore, Roma, Italy;(2) Istituto di Chimica, Universita' Cattolica del Sacro Cuore, Roma, Italy;(3) Centraalbureau voor Schimmelcultures, Baarn, The Netherlands
Abstract:A mycotoxin, confirmed by chemical, physical and spectroscopic data as the PR toxin described by Ru-Dong Wei and coll. (15) has been isolated from culture filtrates of Penicillium roqueforti Thom. Factors affecting the toxin and mycelium production, acute and chronic toxicity in experimental animals and the frequency of toxinogenesis of 21 isolates of P. roqueforti (including a brown mutant) isolated from different materials, foods especially, were also studied. An hypothesis on the absence of PR toxin in cheeses fermented with P. roqueforti is also advanced.
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