A Trichostatin A (TSA)/Sp1-mediated mechanism for the regulation of SALL2 tumor suppressor in Jurkat T cells期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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A Trichostatin A (TSA)/Sp1-mediated mechanism for the regulation of SALL2 tumor suppressor in Jurkat T cells

Authors:	Matías I Hepp David Escobar Carlos Farkas Viviana E Hermosilla Claudia Álvarez Roberto Amigo José L Gutiérrez Ariel F Castro Roxana Pincheira

Institution:	Departamento de Bioquímica y Biología Molecular, Facultad Cs. Biológicas, Universidad de Concepción, Chile

Abstract:

Keywords:	AP4 Activating Protein 4 BAX Bcl-2-associated X protein Brd4 Bromodomain-containing protein 4 Brg1 Brahma-related gene-1 2 Cys2-His2 zinc finger CBP CREB-binding protein CDKN2A Cyclin-Dependent Kinase Inhibitor 2A gene CDKN1A Cyclin-Dependent Kinase Inhibitor 1A gene ChIP Chromatin immunoprecipitation c-MYC v-myc avian myelocytomatosis viral oncogene homolog CRISPR/Cas9 clustered regularly interspaced short palindromic repeats/CRISPR associated 9 DNMT1 DNA (cytosine-5) methyltransferase 1 E1 Exon 1 E1A Exon 1A EK1 Ethanolamine kinase 1 HDAC Histone deacetylase iMEFs immortalized mouse embryonic fibroblasts MEFs mouse embryonic fibroblasts NGF Nerve growth factor NuRD Nucleosome Remodeling and Deacetylase P1 promoter 1 P2 promoter 2 p16INK4a cyclin-dependent kinase inhibitor 2A p21WAF/CIP cyclin-dependent kinase inhibitor 1 or CDK interacting protein 1 p53 tumor suppressor protein PC12 cells pheochromocytoma of the rat adrenal medulla cells RNA Ribonucleic acid PMAIP1 Phorbol-12-myristate-13-acetate-induced protein 1 SALL Spalt-like SP/KLF specificity protein/Krüppel-like factor Sp1 specificity protein 1 Lys703 Lysine 703 SKOV3 SK-ovary adenocarcinoma cells SV40 Simian Virus 40 SWI/SNF SWItch/Sucrose Non-Fermenting TSA Trichostatin A WT1 Wilms tumor 1 ZO-2 Zonula Occludens-2 SALL2 Sp1 TSA Cell death Jurkat T cells
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