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Nerve elements of the heart of the rat after right-sided vagotomy
Authors:E R Pavlovich  V N Shvalev
Abstract:A quantitative electron microscopical investigation of the sinus node of the atrioventricular His' bundle and of the perinodal working myocardium in intact rats and 7, 15 and 30 days after right-sided vagotomy has revealed variable character of changes in the neural elements of the zones mentioned. Certain ultrastructural rearrangements in the neural apparatus are described; they reflect a combination of destructive and regenerative processes in the heart under vagotomy. Thirty days after the operation, regeneration of the neural elements in the sinoauricular area is of restorative and in the atrioventricular area--of excess character. The data are presented on dynamics of changes in the diameter of the amyelinated neural fibers in the cardiac areas investigated. Participation of both nervi vagi in innervation of the main and additional pacemakers of the organ is discussed.
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