Echinococcus granulosus: Distribution of hydatid fluid antigens in tissues of the larval stage: I. Localization of the specific antigen of hydatid fluid (antigen 5) |
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Authors: | L Yarzabal H Dupas D Bout A Capron |
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Institution: | Service d''Immunologie et de Biologie Parasitaire de la Faculté de Médecine et de l''Institut Pasteur, 59000 Lille, France |
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Abstract: | The indirect immunofluorescent test employing a monospecific antiserum has been used to detect the tissue localization of Echinococcus granulosus specific antigen “5.”The antigen was revealed in the inner portion of the germinal “membrane” and in the parenchyma of the protoscoleces. In these stages, it was also demonstrated fixed to the walls of some collecting ducts.It is postulated that the synthesis of the antigen “5” may occur in specialized cells of both the germinal “membrane” and the protoscoleces of the hydatid cysts.The osmoregulatory system of E. granulosus larvae seems to be involved in the transfer of the substance to the cystic cavity. |
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Keywords: | Cestoda Helminth Parasite Immunology Antigenicity Antigens localization Immunofluorescence test Hydatidosis |
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