Incompatibility between bacteriophage lambda and the sex factor F |
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Authors: | Michael German Michael Syvanen |
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Affiliation: | Microbiology and Molecular Genetics, Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115 USA |
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Abstract: | Defective lambda plasmids, either λdv or λN, interfere with the replication of the Escherichia coli sex factor F. The incompatibility between these two plasmids is considered due to the P protein of lambda, since non-lambda replicons into which the lambda P gene has been cloned inhibit F replication. The inhibitory effect of the P protein on F replication is reduced in bacteria with the dnaB mutation grpB. This implies that the interference by lambda P protein is mediated, at least in part, through the E. coli dnaB product. |
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Keywords: | To whom correspondence should be addressed. |
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