Effects of frequency of the tones on auditory event related potentials in monkeys (Macaca fuscata) under various hypobaric hypoxia conditions of simulated high altitudes |
| |
Authors: | Mitsuro Kida Hiroshi Abe Kiyoaki Matsubayashi Tetsuro Matsuzawa |
| |
Affiliation: | (1) Research Institute of Environmental Medicine, Nagoya University, 464-01 Nagoya, Aichi, Japan;(2) Primate Research Institute, Kyoto University, 484 Inuyama, Aichi, Japan |
| |
Abstract: | Changes in auditory event related potentials (ERPs) as a function of frequency of tones ranging from 500 Hz to 8,000 Hz were examined under various hypobaric hypoxia conditions of simulated high altitudes up to 6,000 m. A sequence of P1-N1-P2 components, corresponding to those of the human subject, was observed with the monkey's ERPs. These component amplitudes changed as a function of frequency of tone. The relationship revealed an inverted U curve with a maximum amplitude at a tone of 2,000 Hz. The following results under hypoxia were noted: marked reduction of amplitude in ERPs induced by hypoxia linked only to a tone's particular frequency, especially for 2,000 Hz. The delay of latency in the respective components of the ERPs was dependent on the degree of hypoxia. These findings seem to suggest the anatomical bases of the neural generators contributing to each component of the ERPs. This work was supported by the Cooperation Research Program, Primate Research Institute, Kyoto University. |
| |
Keywords: | Auditory event related potentials Monkey Hypobaric hypoxia Simulated high altitude |
本文献已被 SpringerLink 等数据库收录! |
|