The Role of the Initial State in the Response of the Hemostasis System to Double Exercise

Changes in the hemostasis system were studied in males with a high working capacity when they performed the same dosed double stress exercise test with moderate (N₁ = 1.4 W/kg, t₁ = 6.93 min) and high (N₂ = 2.96 W/kg, t₂ = 3.15 min) intensity with a 1-h interval between. The direction and the magnitude of changes in the main variables of blood coagulation, anticoagulants, and blood and plasma fibrinolytic activity under the influence of exercise were shown to correlate with the initial state of the system. At high values of the variables before the beginning of muscular activity, work results in their decrease, and at low values, in their increase. Previous work increases the dependence of changes in blood coagulation on its initial value upon repeat exercise, without influencing the relationship between alterations in the fibrinolytic activity of whole blood and its value before exercise. Double loading reveals closer relations between the initial values of blood coagulation, anticoagulants, and fibrinolysis and their changes due to work. It was concluded that, on the basis of the correlations presented, it is possible to predict with high probability the direction and the magnitude of hemocoagulant and fibrinolytic response to physical activity in the group of subjects studied.