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Physical education - new technologies for mapping plant genomes |
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| Authors: | Waugh Robert Dear Paul H Powell Wayne Machray Gordon C |
| Institution: | a Scottish Crop Research Institute, Invergowrie, Dundee, UK DD2 5DA b MRC Laboratory of Molecular Biology, Protein and Nucleic Acid Chemistry Division, Cambridge, UK CB2 2QH |
| Abstract: | Locating DNA sequences to specific chromosomal segments is essential for associating genes with phenotypes. It is routinely achieved by segregation analysis using meiotic mapping populations that have also been used to collect phenotypic information. However, meiotic mapping is struggling to cope with the shear volume of sequences emerging from high-throughput (HTP) gene-discovery programs. We describe two approaches, Radiation Hybrid and ‘HAPPY’ mapping, which, in conjunction with meiotic mapping, represent valuable HTP tools in the quest to link genes to phenotypes. |
| Keywords: | radiation hybrids HAPPY mapping physical mapping |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |