Softwares and methods for estimating genetic ancestry in human populations |
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| Authors: | Yushi Liu Toru Nyunoya Shuguang Leng Steven A Belinsky Yohannes Tesfaigzi Shannon Bruse |
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| Affiliation: | 1. Lovelace Respiratory Research Institute, 2425 Ridgecrest Dr. S.E, Albuquerque, NM, 87108, USA
2. VA Medical Center, Albuquerque, NM, USA
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| Abstract: | The estimation of genetic ancestry in human populations has important applications in medical genetic studies. Genetic ancestry is used to control for population stratification in genetic association studies, and is used to understand the genetic basis for ethnic differences in disease susceptibility. In this review, we present an overview of genetic ancestry estimation in human disease studies, followed by a review of popular softwares and methods used for this estimation. |
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