Reactive oxygen species and sperm cells |
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Authors: | Dorota?Sanocka Email author" target="_blank">Maciej?KurpiszEmail author |
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Institution: | (1) Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland |
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Abstract: | There is a dynamic interplay between pro- and anti-oxidant substances in human ejaculate. Excessive reactive oxygen species
(ROS) generation can overwhelm protective mechanism and initiate changes in lipid and/or protein layers of sperm plasma membranes.
Additionally, changes in DNA can be induced. The essential steps of lipid peroxidation have been listed as well as antioxidant
substances of semen. A variety of detection techniques of lipid peroxidation have been summarized together with the lipid
components of sperm membranes that can be subjected to stress. It is unsolved, a threshold for ROS levels that may induce
functional sperm ability or may lead to male infertility. |
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Keywords: | |
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