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SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive
Authors:Libert Sergiy  Pointer Kelli  Bell Eric L  Das Abhirup  Cohen Dena E  Asara John M  Kapur Karen  Bergmann Sven  Preisig Martin  Otowa Takeshi  Kendler Kenneth S  Chen Xiangning  Hettema John M  van den Oord Edwin J  Rubio Justin P  Guarente Leonard
Affiliation:1 Paul F. Glenn Laboratory, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
2 HHMI/Harvard Department of Stem Cell and Regenerative Biology, Cambridge, MA 02138, USA
3 Beth Israel Deaconess Medical Center and Department of Medicine and Harvard Medical School, Boston, MA 02115, USA
4 Department of Medical Genetics, University of Lausanne, and Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland
5 Department of Psychiatry, Centre Hospitalier Universitaire Vaudois, Lausanne 1011, Switzerland
6 Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA 23298, USA
7 Center for Biomarker Research and Personalized Medicine, Department of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA
8 Quantitative Sciences, GlaxoSmithKline R&D, Stevenage SG1 2NY, UK
Abstract:
Keywords:
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