A hormone sends instant messages to the genome |
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| Authors: | Prokesch Andreas Lazar Mitchell A |
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| Institution: | 1 Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
2 Institute for Genomics and Bioinformatics, Graz University of Technology, A-8010 Graz, Austria |
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| Abstract: | Accurate chromosome segregation during mitosis and meiosis is essential for cell viability. Two papers in this issue of Cell (Kitajima et al., 2011; Magidson et al., 2011) describe chromosome movements during cell division with unprecedented accuracy, revealing previously unrecognized features of chromosome spindle alignment and paving the way to quantitative phenotypic and mechanistic analyses of chromosome alignment during prometaphase. |
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