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Interference with the p53 family network contributes to the gain of oncogenic function of mutant p53 in hepatocellular carcinoma
Authors:Tobias Schilling  Gerry Melino  Peter H. Krammer  Moshe Oren
Affiliation:a Department of Internal Medicine I and Clinical Chemistry, University Hospital, Heidelberg, Germany
b Department of Internal Medicine IV, Hepatology and Gastroenterology, University Hospital, Heidelberg, Germany
c Biochemistry Laboratory, IDI-IRCCS, c/o Department of Experimental Medicine and Biochemical Sciences, University of Rome, Rome, Italy
d Medical Research Council, Toxicology Unit, Hodgkin Building, P.O. Box 138, Lancaster Road, University of Leicester, Leicester LE1 9HN, United Kingdom
e Tumor Immunology Program, German Cancer Research Center (DKFZ), Heidelberg, Germany
f The Weizmann Institute, Department of Molecular Cell Biology, Rehovot 76100, Israel
Abstract:
Keywords:p53   p63   p73   Apoptosis   Hepatocellular carcinoma   p53 gain-of-function
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