5'-halogenated analogs of oxymorphindole |
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| Authors: | Metcalf Matthew D Coop Andrew |
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| Affiliation: | Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 Penn Street, Baltimore, MD 21201, USA. |
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| Abstract: | The presence of a 6,7-fused indole group in the indolomorphinans was considered to be responsible for the delta opioid selectivity for this class of ligands. Herein is shown that 5'-halogenated analogs of oxymorphindole are opioids with little selectivity for delta receptors over mu opioid receptors. |
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