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Metabolites produced by probiotic Lactobacilli rapidly increase glucose uptake by Caco-2 cells
Authors:Arun K Rooj  Yasuhiro Kimura  Randal K Buddington
Institution:(1) Integrative Biomedical Sciences, University of Alabama at Birmingham, 35205 Birmingham, AL, USA;(2) Department of Food and Nutrition, Beppu University, 874-8501, 82 Kita-Ishigaki, Beppu, Oita, Japan;(3) Department of Health and Sport Sciences, University of Memphis, 38152-3480 Memphis, TN, USA
Abstract:

Background  

Although probiotic bacteria and their metabolites alter enterocyte gene expression, rapid, non-genomic responses have not been examined. The present study measured accumulation of tracer (2 μM) glucose by Caco-2 cells after exposure for 10 min or less to a chemically defined medium (CDM) with different monosaccharides before and after anaerobic culture of probiotic Lactobacilli.
Keywords:
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