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Structure of the capsular antigen of Neisseria meningitidis serogroup H |
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| Authors: | A van der Kaaden J I van Doorn-van Wakeren J P Kamerling J F Vliegenthart R H Tiesjema |
| Abstract: | The capsular polysaccharide of Neisseria meningitidis serogroup H is composed of the following repeating unit, Gro = glycerol; (formula; see text) Partial O-acetylation of the D-Galp moieties is found for C-2 (21%) and C-3 (57%). The structural elucidation of the biopolymer is based on sugar analysis, methylation analysis, partial acid hydrolysis, using gas-liquid chromatography/mass spectrometry studies, and NMR spectroscopy with 1H, 13C and 31P. |
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