Repair of double-strand breaks in a temperature conditional radiation-sensitive mutant of Saccharomyces cerevisiae |
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| Affiliation: | 1. Institute for Frontier Materials, Deakin University, Geelong, VIC 3220, Australia;2. Monash Centre for Electron Microscopy, Department of Materials Science and Engineering, Monash University, Clayton, VIC 3800, Australia;3. Center for Nanophase Materials Sciences, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6139, USA |
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| Abstract: | Neutral sucrose-gradient profiles of rad54-3 cells illustrate that diploid rad54-3 cells are unable to repair double-strand breaks at the restrictive temperature, 36°, but are capable of repair at the permissive temperature, 23°. Rad54-3 strains are temperature conditional for double-strand repair. |
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