Sister-chromatid exchanges in mouse embryos after exposure to ultrasound in utero |
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| Affiliation: | 1. Department of Biological Sciences, University of Arkansas, Fayetteville, AR, United States;2. Howard Hughes Medical Institute and Developmental Biology Program, Sloan Kettering Institute, New York, NY, United States;1. Kedge Business School, Domaine de Luminy, BP 921, 13288 Marseille Cedex 9, France;2. DAN Management and Organizational Studies, University of Western Ontario, Social Science Centre Room 4315, 1151 Richmond Street, London, Ontario N6A 5C2, Canada |
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| Abstract: | Mouse embryos at 2 stages of development were exposed to ultrasound. The bone-marrow cells of the mother, the whole embryo, and the embryonic liver cells were analyzed. There was no consistent increase of sister-chromatid exchanges. Furthermore, the thermal effect of ultrasound did not appear to influence the frequency. Thus, ultrasound doses much higher than those used in clinical diagnosis do not induce cytogenetic damage as assayed by sister-chromatid exchanges. |
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