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Oxidative stress: Protein folding with a novel redox switch.
Authors:L W Ruddock  P Klappa
Affiliation:Research School of Biosciences, University of Kent, Canterbury CT2 7NJ, UK.
Abstract:A novel cellular response to oxidative stress has been discovered, in which the activity of a molecular chaperone, Hsp33, is modulated by the environmental redox potential. This provides a rapid first defence mechanism against the potentially very harmful toxic effects of oxidative stress.
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