Oxidative stress: Protein folding with a novel redox switch. |
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Authors: | L W Ruddock P Klappa |
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Affiliation: | Research School of Biosciences, University of Kent, Canterbury CT2 7NJ, UK. |
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Abstract: | A novel cellular response to oxidative stress has been discovered, in which the activity of a molecular chaperone, Hsp33, is modulated by the environmental redox potential. This provides a rapid first defence mechanism against the potentially very harmful toxic effects of oxidative stress. |
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