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Influence repeated stress on immune responciveness and monooxigenase activity of normotensive and hypertensive rats
Authors:Tseĭlikman V E  Kozochkin D A  Markel' A L  Tseĭlikman O B  Sibiriak S V  Sinitskiĭ A I  Sysakov D A  Simbitrsev A S
Abstract:Repeated stress led to antipodal directions in immune system and cytochrome P450 activities of normotensive and hypertensive rats. Enhancement of the Reaction of Delayed Hypersensitivity, suppression of cytochrome P450-mediated monooxigenase activities were observed in Wistar rats. On the contrary, in the NISAG decrease of the Reaction Delayed Hypersensitivity, elevation of cytochrome P450-mediated monooxigenase activities were observed, as comparison with Wistar rats.
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