The binding of organic ions to phospholipid bilayers |
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Authors: | B.A. Levine J. Sackett R.J.P. Williams |
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Affiliation: | Inorganic Chemistry Laboratory, South Parks Road, Oxford OX1 3QR U.K. |
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Abstract: | The binding of organic anions and cations, mainly tetraphenylboride and tetraphenylarsonium, to phospholipid membranes has been studied using an NMR method. Binding is appreciable and is affected by cholesterol in the membrane and counterions in solution. The passage of the organic anions through the membrane has also been followed. These measurements indicate that it is naive to use organic anions to measure membrane potentials in a simple manner. |
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Keywords: | Organic ion binding Phospholipid (Bilayer) |
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