Effect of estrogens on boar sperm capacitation <Emphasis Type="Italic">in vitro</Emphasis> |
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Authors: | Lukas Ded Pavla Dostalova Andriy Dorosh Katerina Dvorakova-Hortova Jana Peknicova |
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Institution: | (1) Laboratory of Diagnostics for Reproductive Medicine, Institute of Biotechnology, Academy of Sciences of the Czech Republic, v. v. i., Prague, Czech Republic;(2) Department of Zoology, Faculty of Science, Charles University, Prague, Czech Republic |
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Abstract: | Background Mammalian sperm must undergo a series of controlled molecular processes in the female reproductive tract called capacitation
before they are capable of penetrating and fertilizing the egg. Capacitation, as a complex biological process, is influenced
by many molecular factors, among which steroidal hormone estrogens play their role. Estrogens, present in a high concentration
in the female reproductive tract are generally considered as primarily female hormones. However, there is increasing evidence
of their important impact on male reproductive parameters. The purpose of this study is to investigate the effect of three
natural estrogens such as estrone (E1), 17beta-estradiol (E2) and estriol (E3) as well as the synthetical one, 17alpha-ethynylestradiol
(EE2) on boar sperm capacitation in vitro. |
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