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MMP-9 induces CD44 cleavage and CD44 mediated cell migration in glioblastoma xenograft cells
Authors:Chetty Chandramu  Vanamala Sravan K  Gondi Christopher S  Dinh Dzung H  Gujrati Meena  Rao Jasti S
Affiliation:
  • a Program of Cancer Biology, Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, One Illini Drive, Peoria, IL 61605, USA
  • b Department of Neurosurgery, University of Illinois College of Medicine at Peoria, One Illini Drive, Peoria, IL 61605, USA
  • c Department of Pathology, University of Illinois College of Medicine at Peoria, One Illini Drive, Peoria, IL 61605, USA
  • Abstract:
    Keywords:MMP-9, matrix metalloproteinase-9   CD44ECD, CD44 extracellular domain   CD44ICD, CD44 intracellular domain   GBM, Glioblastoma   hMMP-9, purified human MMP-9   rhCD44, recombinant human CD44   APMA, p-aminophenylmercuric acetate   HA, hyaluronic acid   SV, scrambled vector   IHC, immunohistochemical   CNS, central nervous system   ECM, Extracellular matrix
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