Repeated extinction and reversal learning of an approach response supports an arousal-mediated learning model |
| |
Authors: | Podlesnik Christopher A Sanabria Federico |
| |
Institution: | a Department of Pharmacology, University of Michigan Medical School, 3415 MSB I, 1301 Catherine Street, Ann Arbor, MI 48109-5632, United States b Arizona State University, Department of Psychology, P.O. Box 871104, Tempe, AZ 85287-1104, United States |
| |
Abstract: | We assessed the effects of repeated extinction and reversals of two conditional stimuli (CS+/CS−) on an appetitive conditioned approach response in rats. Three results were observed that could not be accounted for by a simple linear operator model such as the one proposed by Rescorla and Wagner (1972): (1) responding to a CS− declined faster when a CS+ was simultaneously extinguished; (2) reacquisition of pre-extinction performance recovered rapidly within one session; and (3) reversal of CS+/CS− contingencies resulted in a more rapid recovery to the current CS− (former CS+) than the current CS+, accompanied by a slower acquisition of performance to the current CS+. An arousal parameter that mediates learning was introduced to a linear operator model to account for these effects. The arousal-mediated learning model adequately fit the data and predicted data from a second experiment with different rats in which only repeated reversals of CS+/CS− were assessed. According to this arousal-mediated learning model, learning is accelerated by US-elicited arousal and it slows down in the absence of US. Because arousal varies faster than conditioning, the model accounts for the decline in responding during extinction mainly through a reduction in arousal, not a change in learning. By preserving learning during extinction, the model is able to account for relapse effects like rapid reacquisition, renewal, and reinstatement. |
| |
Keywords: | Pavlovian conditioned approach Extinction Reversal learning Arousal Nose poke Rat |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|