A methodology for numerically analysing the hepatic artery haemodynamics during B-TACE: a proof of concept |
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| Authors: | Jorge Aramburu Raúl Antón Alejandro Rivas Juan Carlos Ramos Gorka S. Larraona Bruno Sangro |
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| Affiliation: | 1. Universidad de Navarra, TECNUN Escuela de Ingenieros, Donostia-San Sebastián, Spain;2. Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain;3. Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain;4. Clínica Universidad de Navarra, Pamplona, Spain;5. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Pamplona, Spain |
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| Abstract: | Balloon-occluded transarterial chemoembolisation (B-TACE) is an intraarterial transcatheter treatment for liver cancer. In B-TACE, an artery-occluding microballoon catheter occludes an artery and promotes collateral circulation for drug delivery to tumours. This paper presents a methodology for analysing the haemodynamics during B-TACE, by combining zero-dimensional and three-dimensional modelling tools. As a proof of concept, we apply the methodology to a patient-specific hepatic artery geometry and analyse two catheter locations. Results show that the blood flow redistribution can be predicted in this proof-of-concept study, suggesting that this approach could potentially be used to optimise catheter location. |
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| Keywords: | Liver cancer B-TACE haemodynamics computational fluid dynamics 0D modelling 3D modelling |
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