Using of electrochemical methods for studying of metallothionein content in the human blood serum of a patient poisoned by lead and treated by platinum |
| |
| Authors: | Petrlová Jitka Blastík Ondrej Pr?sa Richard Kukacka Jirí Pot?sil David Mikelová Radka Adam Vojt?ch Zehnálek Josef Kizek René |
| |
| Institution: | Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University of Agriculture and Forestry, Zemedelská 1, Brno, CZ-613 00, Czech Republic. kizek@sci.muni.cz. |
| |
| Abstract: | Metallothioneins belong to the group of intracellular, high molecular and cysteine-rich proteins whose content increase with increasing concentration of a heavy metal. Here we applied the adsorptive transfer stripping differential pulse voltammetry Brdicka reaction for the determination of metallothionein in human blood serum of patient poisoned by lead and/or treated by platinum. The increased metallothionein concentrations in both cases were observed. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
