Applications of new laboratory marker assays in neurological diagnoses - a pilot study |
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Authors: | Stejskal David Vavrousková Jitka Mares Jan Urbánek Karel |
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Affiliation: | Department of Laboratory Medicine, Sternberk Hospital, Czech Republic. david.stejskal@quick.cz |
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Abstract: | 225 consecutive patients with different neurological diseases and 101 individuals as the control were examined between 2002-2004. Cystatin C, arginase-I, tau-protein and beta-amyloid were measured. Individuals with CNS inflammation had significantly lower Cystatin-C index (CSF/serum) values. There was no diagnostic significance of the Arginase-I assay in CSF was verified. The CSF tau-protein/beta-amyloid index was shown to be a sufficient efficacy for neurodegenerative disease diagnosis. |
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