TAK1-mediated transcriptional activation of CD28-responsive element and AP-1-binding site within the IL-2 promoter in Jurkat T cells |
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Authors: | Sakurai Hiroaki Singhirunnusorn Pattama Shimotabira Emi Chino Atsushi Suzuki Shunsuke Koizumi Keiichi Saiki Ikuo |
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Affiliation: | Division of Pathogenic Biochemistry, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Toyama 930-0194, Japan. hsakurai@ms.toyama-mpu.ac.jp |
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Abstract: | |
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Keywords: | TAK1, transforming growth factor-β-activated kinase 1 TAB1, TAK1-binding protein 1 IL-2, interleukin-2 TCR, T cell receptor MAPK, mitogen-activated protein kinase JNK, c-Jun NH2-terminal kinase ERK, extracellular signal-related kinase MAP3K, MAPK kinase kinase AP-1, activator protein-1 NF-κB, nuclear factor-κB IKK, IκB kinase RE/AP, CD28-response element/AP-1-binding site TPA, 12-O-tetradecanoylphorbol-13-acetate |
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