肝移植术后急性肾功能衰竭的相关因素的临床分析

目的：探讨肝移植术后并发急性肾功能衰竭（ARF）的相关因素，为肝移植术后ARF的预防和治疗提供参考。方法：回顾性分析了2005年1月-2010年10月在我院行肝移植术的98例患者的临床资料，对术后并发ARF的相关因素进行分析。结果：98例行肝移植术后发生ARF13例，发生率为13．27％。单因素分析显示术前血尿素氮CBUN）、术前血清肌酐（Scr）、术前血清白蛋白（Alb）、手术时间、失血量与ARF的发生有关（P〈0．05）。多因素Logistic回归法分析表明，术前Ser和BUN是肝移植术后并发ARF的危险因素。结论：术前血BUN、血清Scr、血清Alb、手术时间和失血量是肝移植术后并发ARF主要因素，而术前Scr和BUN水平升高是肝移植术后并发ARF的危险因素。对上述因素加以重点评估和合理控制，可以控制肝移植术后ARF的发生。

Clinical Analysis of Related Factors in Patient with Acute Renal Failure after Liver Transplantation

Objective： To investigate the related factors in patient with acute renal failure （ARF） after liver transplantation and provide reference for prevention and treatment of ARF after liver transplantation, Mothods： A total of 98 patients, undergoing liver transplantation from January 2005 to October 2010, were selected, analyzing and screening the related factors of acute renal failure after liver transplantation by Logistic. Results： 13 cases of 98 patients occurred ARF, the incidence rate of ARF was 13.27%. The single-factor analysis showed that the priorsurgery blood BUN, pfiorsurgery serum Scr, priorsurgery serum Alb, operative time and blood loss had certain degree of contact with the incidence of ARF after liver transplantation （P〈0.05）. Multivariate Logistic regression analysis showed that the priorsurgery serum Scr and blood BUN levels increased were risk factors of incidence of ARF after liver transplantation. Conclusion： The priorsurgery blood BUN, priorsurgery serum Scr, priorsurgery serum Alb, operative time and blood loss are the related factors of incidence of ARF after liver transplantation. The priorsurgery serum Scr and blood BUN levels were risk factors of incidence of ARF after liver transplantation. Assessment and control of these factors can reduce the incidence of ARF after liver transplantation.