| 慢性炎症与动脉粥样硬化关系的研究进展 |
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| 引用本文： | 闫凤,陈压西,赵长海.慢性炎症与动脉粥样硬化关系的研究进展[J].生物磁学,2011(20):3964-3967. |
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| 作者姓名： | 闫凤 陈压西 赵长海 |
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| 作者单位： | [1]第四军医大学西京医院,陕西西安710032 [2]重庆医科大学脂质研究中心,重庆400016 |
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| 基金项目： | 国家自然科学基金（No.30871159,30971389,30772295,重点项目No.30530360）,重庆市自然科学基金重点项目（CSTC,2008BA5016） |
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| 摘 要： | 动脉粥样硬化（atherosclerosis，AS）的发病机制非常复杂，对其研究经历了一个半世纪，直到1999年Ross提出”动脉粥样硬化是一种炎症性疾病”，各种炎症细胞和炎症因子参与动脉粥样硬化的发生和发展过程。已有众多的基础和临床研究都证实炎症在AS中的重要作用，但仍需要对AS发生发展的深入研究，使我们更准确认识和有效的防治AS。本文就近年来慢性炎症与动脉粥样硬化关系的研究进展作一综述。
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| 关 键 词： | 炎症 动脉粥样硬化 炎症介质 |
Progress of Chronic Systemic Inflammation and Atherosclerosis |
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| YAN Feng CHEN Ya-xi,ZHAO Chang-hai.Progress of Chronic Systemic Inflammation and Atherosclerosis[J].Biomagnetism,2011(20):3964-3967. |
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| Authors: | YAN Feng CHEN Ya-xi ZHAO Chang-hai |
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| Institution: | 1 Xijing hospital, fourth military medical university Xi＇an 710032 China; 2 Lipid Research Center of Chongqing Medical University Chongqing 400016 China) |
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| Abstract: | The pathogenesis of atherosclerosis （AS） which has been researched more than one and half centuries is extremely complicated. Until 1999, Ross stated that ＂atherosclerosis is an inflammatory disease＂, various kinds of inflammatory cells and factors took part in the progression of occurrence and development. There are many basic and clinical researches have demonstrated the important role of inflammation in AS, but more lucubrates are needed for exactly recognition and effective prevention and treatment of AS. This review summarizes the new progression of the relation between chronic systemic inflammation and atherosclerosis. |
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| Keywords: | Inflammation atherosclerosis inflammatory mediator |
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