大豆卵磷脂对小鼠的抗疲劳和抗氧化作用研究

目的：研究大豆卵磷脂的抗疲劳及抗氧化作用。方法：小鼠经口给予大豆卵磷脂30天后，采用负重游泳实验，观察记录小鼠游泳死亡时间；检测血清尿素氮、肝糖原；测定血清和肝匀浆超氧化物歧化酶（SOD）活性、谷胱甘肽过氧化物酶（GSH—Px）活力、丙二醛（MDA）含量。结果：给予大豆卵磷脂后，与对照组相比，实验组小鼠负重游泳时间明显延长，肝糖原消耗量减少，降低运动后血清尿素氮水平（P〈0．05）；升高小鼠血清和肝匀浆SOD活性及GSH-Px活力，降低MDA的含量（P〈0．05）。结论：大豆卵磷脂具有抗疲劳和抗氧化作用。

Anti-Fatigue and Anti-oxidation Effects of Soybean Lecithin in Mice

Objective： To investigate the anti-fatigue and anti-oxidation effect of Soybean Lecithin. Methods： Ninety mice were given randomly divided into high Soybean Lecithin group. Soybean Lecithin was given orally. After 30 days, weight-loaded swimming test were performde to observed the death time. Serum urea nitrogen and glycogen were tested. The activities of superoxide dismutase （SOD）, malondialdehyde （MDA）, and glutathione peroxidase （GSP-Px） in serum and liver was measured. Results： Compared with control group, Soybean Lecithin prolonged the swimming time, increased the consumption of hepatic glycogen, and decreased the level of urea nitrogen in serum. The SOD activity and GSP-Px in Soybean Lecithin group significantly increased and the concentrations of MDA sig- nificantly decreased. Conclusion： Soybean Lecithin can improve sporting endurance and delay fatigue, and also has antioxidative effect.