| PTEN蛋白表达与前列腺癌病理分期的关系 |
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| 引用本文： | 杨侠,杨军岭,王珏,王磊,付强.PTEN蛋白表达与前列腺癌病理分期的关系[J].生物磁学,2011(22):4267-4268. |
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| 作者姓名： | 杨侠 杨军岭 王珏 王磊 付强 |
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| 作者单位： | [1]第四军医大学唐都医院医疗科,陕西西安710038 [2]解放军323医院药剂科,陕西西安710038 [3]第四军医大学唐都医院感染科,陕西西安710038 [4]第四军医大学唐都医院泌尿外科,陕西西安710038 |
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| 摘 要： | 目的：探讨PTEN蛋白在前列腺癌组织中的表达及其临床意义。方法：应用免疫组织化学S-P方法，检测前列腺癌及良性前列腺增生组织中PTEN蛋白的表达。结果：PTEN蛋白表达阳性随肿瘤细胞病理分级、临床分期的增高，PTEN蛋白阳性表达率降低。结论：PTEN蛋白异常表达在前列腺癌的进展中有重要作用，检测PTEN蛋白的表达有助于判断病情及预后。
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| 关 键 词： | 前列腺癌 PTEN蛋白 免疫组织化学 |
PTEN Protein Expression and the Relationship between Prostate Cancer Patho-Staging |
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| YANG Xia,YANG Jun-ling,WANG Jue,WANG Lei,FU Qiang.PTEN Protein Expression and the Relationship between Prostate Cancer Patho-Staging[J].Biomagnetism,2011(22):4267-4268. |
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| Authors: | YANG Xia YANG Jun-ling WANG Jue WANG Lei FU Qiang |
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| Institution: | 1 Department of Medical Treatment Tangdu Hospital, The Fourth Military Medical University, Xi＇an 710038, China; 2 The Department of Phannaey 323 Hospital, The Chinese People＇s Liberation Army, Xi＇an 710038, China; 3 Department of Contagion Tangdu Hospital, The Fourth Military Medical University, Xi＇an 710038, China; 4 Department of Urology Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi＇an 710038, China) |
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| Abstract: | Objective： Investigate Of PTEN protein express and its clinical significance in prostate cancer tissues. Methods： Immunohistochemical S-P method detection PTEN protein in Prostate cancer and benign prostatic hyperplasia. Results： PTEN protein express lower with higher pathological grade and clinical stage. Conclusion： Abnormal expression of PTEN protein in prostate cancer progression plays an important role, Detect the expression of PTEN protein helps to determine the severity and prognosis. |
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| Keywords: | Prostate cancer PTEN protein Immunohistochemical |
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