脂肪酶抑制剂应用于抗肥胖的研究进展

肥胖易引发各种慢性代谢疾病，肥胖在全球的迅速流行引起了人们的关注。脂肪酶抑制剂作为一种作用于肠道内的减肥药物，不进入血液，不会产生中枢神经性副作用，不影响矿物质代谢，是近年来研究的热点。而各种植物提取物作为脂肪酶抑制剂的来源，具有非常巨大的潜力，以其更高的安全性，更广泛的来源，日后必将在新型减肥药品或保健品开发中占有重要的一席之地。本文主要就脂肪酶抑制剂的性质和应用于减肥领域的进展作一简要综述。

Recent Advances of Lipase Inhibitor in the Application of Anti-obesity

On a global scale, obesity has reached epidemic proportions and is a major contributor to the global burden of chronic disease. Lipase inhibitors show the anti-obesity activity in the intestine without being absorbed into blood. Moreover, lipase inhibitors would not cause any neuropathic side-effect or mineral metabolic turbulence, which make them safer during anti-obesity treatment. Extracts from plants have an enormous potential to be the source of lipase inhibitors, which has caught researcher＇s focus and will become a new therapy for anti-obesity. Here we briefly reviewed the property of lipase inhibitor and its application in anti-obesity.