孕妇孕前体重指数与妊娠期糖代谢异常发病相关性的研究

目的：探讨孕前体重指数与妊娠期糖代谢异常发病及其临床特点的关系。方法：采用病例一对照研究的方法，对孕期在我院进行健康保健确诊为糖代谢异常并已完成分娩的孕妇130例作为病例组，同时随机抽取同期分娩的260例糖代谢正常孕妇作为对照组。用Logistic回归模型对孕前体重指数进行单因素分析；计算其相对危险度。结果：病例组孕妇孕前BMI指数大于25者占80．77％，明显高于对照组的（19．23％），差别有统计学意义（X2=30．469，P〈0．05）。logistic回归结果显示相对于BMI小于25者。BMI〉25组发生糖代谢异常的相对危险度是3．90，95％CI为2．23—6．41。结论：孕妇孕前体重指数是妊娠期糖代谢异常的独立危险因素，因此孕前控制体重指数是降低孕期糖代谢异常发生的关键因素。

A Study of the Relationship between Abnormal Glucose Metabolism During Pregnancy and Progestational BMI

Objective： To determine the relationship of gestational diabetes mellitus （GDM）, gestational impaired glucose tolerance （GIGT） and progestational BMI and clinical characters. Methods： A total of 130 pregnant women, who were diagnosed GDM and GIGT and have completed delivery, were considered as group of case, and 260 pregnant women with normal glucose metabolism, as control. Univariate analysis was used to estimate the odds ratios with 95%CI. Results： The rate of BMI〉25 in cases were 80.77%, which significantly higher than that （19.23%） in control, X2=30.469,P〈0.05. The logistic results showed that BMI was the risk factors of GDM and GIGT, OR=3.90, 95%CI （2.23-6.41）. Conclusion： The pre-pregnancy body mass index may be one independent risk facter of GDM and GIGT. So controlling the BMI before pregnancy will be the key factors of reducing the occurrence of abnormal glucose metabolism during pregnancy.