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Mitochondrial dysfunction in a transgenic mouse model expressing human amyloid precursor protein (APP) with the Arctic mutation
Authors:Annica Rönnbäck  Pavel. F. Pavlov  Mansorah Mansory  Prisca Gonze  Nicolas Marlière  Bengt Winblad  Caroline Graff  Homira Behbahani
Affiliation:1. Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Huddinge, Sweden;2. Department of Geriatric Medicine, Genetics Unit, Karolinska University Hospital, Sweden;3. Division of Neurogeriatrics and Clinical Geriatrics, Huddinge, Sweden
Abstract:
Keywords:Alzheimer Disease  amyloid beta  arctic APP mutation  mitochondria     MMP        ROS   
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